The 2025-26 English Premier League (EPL) season is underway, and if you're looking to get in on the betting action for matchday two, then you've come to the right place. Below, I'll dive into three upcoming matches from a betting perspective and let you know where I'm laying my money on the pitch. Here are my top EPL picks and predictions for Matchday 2’s game Manchester City vs. Tottenham.
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EPL Matchday 2 Picks: Manchester City vs. Tottenham
(Odds courtesy of DraftKings Sportsbook)
Manchester City (-205) vs. Tottenham (+475), DRAW (+380) | O/U 3.5 (+120/-150)
Let's pick it up on Saturday morning, where a couple of unbeaten teams will square off. Manchester City sits atop the table at 1-0-0 with a +4 goal differential, while Tottenham boasts the same record and ranks third on goal differential (+3). Kickoff is scheduled for 7:30 a.m. ET from Etihad Stadium in Manchester.
I'll take a +120 flier to say this contest goes over 3.5 goals. These are two of the more potent offenses in the league, which was exemplified in matchday one when they combined for seven goals. For City, it was a 4-0 decimation of Wolverhampton. The Lilywhites smashed Burnley in a 3-0 match.
After an injury-plagued 2024-25 and simply underwhelming play, this Manchester City team is back to being the juggernaut that we've become accustomed to for years. They have the third-shortest price to win the title (+275), and I expect Erling Haaland, Jeremy Doku, Bernardo Silva, and Co. to keep things rolling this weekend. Both of these clubs averaged 1.7 goals per match last season, and that'll roughly be the mark that we need to hit at the Etihad on Saturday. I think it's doable, and I'm expecting a 3-1 or 2-2 contest.
Pick: Over 3.5 Goals (+120)
