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Western Kentucky Hilltoppers vs. UTSA Roadrunners Odds and Game Pick (2021)

by December 1, 2021
Frank Harris

This is an intriguing matchup for the Conference USA Championship game. UTSA was undefeated while ranking 15th in the nation heading into last week, but the Roadrunners suffered a disappointing 45-23 loss to North Texas. Now that their hopes of an undefeated season have vanished, UTSA will look to pick themselves up and claim the crown of a conference they have dominated for most of the year. 

Meanwhile, Western Kentucky enters this game on a nice hot streak. The Hilltoppers have won seven in a row. Their last loss came against this same UTSA team in a 52-46 shootout on October 9. Needless to say, we could have another entertaining back-and-forth affair on our hands this time around. 

We’ll break down all the betting angles of this Friday evening matchup.

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  • Opening Line: Western Kentucky -2.5
  • Over/Under: 72.5
  • Location: Alamodome in San Antonio, TX
  • Kickoff: 7:00 ET


Is anyone mildly surprised that Western Kentucky is favored in this game? UTSA has been the class of Conference USA this entire season by boasting an 11-1 record. This game will be played in San Antonio as well, which gives a slight boost to the Roadrunners. 

However, you could argue that Western Kentucky has been playing better football as of late. UTSA’s slip up at North Texas serves as crucial evidence to support that claim. Not only is Western Kentucky on a seven-game winning streak, but they have also beaten their opponent by at least two touchdowns in all of those contests. 


  • Western Kentucky is 5-0 ATS in their last five games.
  • UTSA is 9-0 SU in their last nine home games.
  • The total is 4-1 to the OVER in UTSA’s last five games.

Bottom Line 

So what’s the move here? Was UTSA’s loss at North Texas the beginning of a downtrend or just a small speed bump? This should be an entertaining, high-scoring game, but UTSA seems like the right side as a small home underdog. Their rushing attack, which ranks top 40 in the country, should be able to control the game. UTSA will revert to their brand of mistake-free football and pull out the win. 

The Pick: UTSA +2.5


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