UFC 334 has all the storylines you could possibly want out of a pay-per-view. One of the best fighters of all time, Amanda Nunes, is coming out of retirement to fight a former teammate, Kayla Harrison, for the women's bantamweight title. Undefeated heavyweight contender Josh Hokit is playing the heel to perfection leading up to his title fight against champion Ciryl Gane. The only thing left to do is put on the gloves and enter the octagon at Madison Square Garden in New York City. The prelims begin at 5 p.m. EST, while the main card starts at 9 p.m. EST, all on Paramount+.
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UFC 334 Main Card Odds, Picks & Predictions (2026)
(Odds courtesy of DraftKings Sportsbook)
Uros Medic (-155) vs. Kevin Holland (+130)
The second fight on the main card is a welterweight matchup between No. 12 Uros Medic and No. 15 Kevin Holland. Medic is on a roll since his last loss to Punahele Soriano in January 2025. He has four consecutive first-round knockouts over Daniel Rodriguez (April), Geoff Neal (February), Muslim Salikhov, and Gilbert Urbina.
Holland is 29-12 (1 NC) as a professional and 16-12 (1 NC) in the UFC. He is consistently one of the most active fighters on the roster, but has not found a lot of success recently. Holland is 4-6 in his last 10 fights, but has won three of his last five. He recently beat Randy Brown via unanimous decision, but lost to Mike Malott and Daniel Rodriguez before that.
Holland has a 10-inch reach advantage in this matchup. That makes it an interesting matchup, but Medic is an elite kickboxer. Holland has good grappling, but is not a dominant wrestler. He has to find a great position to lock in a submission, and I do not see that happening.
Medic lands 5.77 significant strikes and absorbs 3.40 significant strikes per minute. He lands with 60% accuracy and defends 56% of his opponent's significant strikes. Medic has the power to hurt Holland, but has historically had an above-average chin.
Medic is on a tear and is trending in the right direction. Holland is back-and-forth and does not always show up. He does have tons of experience in the cage, and Medic does not have much time recently due to him winning so quickly. Still, Medic can land power punches against Holland, who does not use his length well.
Bet: Uros Medic (-155)
Kayla Harrison (-170) vs. Amanda Nunes (+142)
There are so many layers to this title fight. Kayla Harrison is putting her belt on the line against former teammate and the greatest female fighter of all time, Amanda Nunes.
Harrison is a two-time Olympic judo gold medalist and 19-1 as a professional in MMA. She is as decorated a combat sports athlete as anyone and has transitioned well to MMA. Harrison spent most of her career in PFL before coming to the UFC, winning all three of her bouts. She won the belt in June 2025 over Julianna Pena via second-round submission.
Nunes is a two-division champion and has fought for the title in her last 12 fights. Her only loss was to Pena, who submitted her in the second round in 2021. Nunes made her professional debut in 2008 and fought twice for Strikeforce in 2011 before it was bought by Zuffa, LLC (the parent company of the UFC).
The obvious concern for Nunes is that she has not fought since June 2023. That was three years and four months ago. Nunes will have moments in this fight, but that is not enough to win a fight against the likes of Harrison.
Harrison is physical, strong, and suffocating. She averages 2.84 takedowns landed per 15 minutes, and that number could be higher. Her control on the mat is elite, and she holds opponents there.
Nunes likely has better striking, especially with her powerful boxing. How does that look after a long layoff? It is going to take some time to find her timing. No matter how much you train, it is impossible to replicate a title fight at Madison Square Garden against a dominant fighter like Harrison.
This fight likely plays out similarly to Harrison's matchup against Ketlen Vieira. Vieira stayed safe on the mat and was able to last all 15 minutes, but Harrison still dominated the fight. Harrison is more active, younger, and in her prime. Nunes and Harrison have a lot of history from their time at American Top Team, but I will not dive into that here. It is an emotional fight for each, but Harrison is the better side in this matchup.
Bet: Kayla Harrison via Decision (+300)
