Skip to main content

Bills vs. Bears: NFL Week 16 Odds, Picks & Predictions (2022)

by December 22, 2022
Bills vs. Bears: NFL Week 16 Odds, Picks & Predictions (2022)

Let’s take a look at our preview and best bet for the NFL Week 16 game Bills vs. Bears.

And check out our predictions for other Week 16 NFL games:


View our Pick of the Day in the BettingPros mobile app (free!) >>

BettingPros Free Upgrade Offer

NFL Week 16 Odds, Picks & Predictions: Bills vs. Bears

Temperatures in the negatives are expected with windy conditions. Luckily, for the Bears, this won’t affect their gameplan too much. Their dual running attack of David Montgomery and Justin Fields has shot up to 9th in DVOA rankings and will be leaned on heavily again here.

The Bills meanwhile, don’t possess an elite running game (ranking 15th in DVOA), but against a Bears defense that has trouble stopping anyone this may not be much of an issue. Wind factors could slow down the Bills’ passing attack but Josh Allen has one of the strongest arms in the league and can make plays when needed against this Chicago team.

Weather conditions are likely to keep this game a low scoring ground affair. As explosive as the run game has been for Chicago, if there’s no threat to throw the ball, Buffalo’s stout defense should be able to contain it. The under is the best play here even with a Bills offense that should still be able to put up some points.

Lean Bills -8.5, u40.5

Whether you’re new to sports betting or a betting pro, our Sports Betting Strategy and Advice page is for you. You can get started with our 101 section — including 10 Sports Betting Tips for Beginners — or head to more advanced strategies — like Key Numbers When Betting Against the Spread — to learn more.

View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>

Join the BettingPros Discord server and chat with betting experts and others making wagers in an active sports betting community!

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts

NFL, Picks